DEMODEXIN - Unresponsive chronic acne/rosacea anti-parasite lotion - 4 oz.
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If you or someone you know has had persistent,
unresponsive acne/rosacea symptoms characterized by
blotchy skin which transmigrates around the face
accompanied by itchiness or a tickling sensation
then the problem is facial mites (Demodex
folliculorum and Demodex brevis). Demodex
brevis is the type that is usually the cause of
deep-seated, long-term problems associated with facial
acne/rosacea and scarring. Scarring may accompany this
condition along with a residual bacterial infection
caused by the detritus of mite infestation for long-term
1. What are Demodex mites?
Demodex Mites, also known as face mites, are not so well
known by the public. They are parasites which live on the
face and in the hair follicles of humans. They can badly
damage the facial skin of humans, usually starting at
middle age when the immune system is weakened and their
population has increased.
There are two existing types: the longer kind, Demodex
folliculorum, which live in the hair follicles and the
short ones, Demodex brevis, which live in the
The mites are invisible to the naked eye, usually
measuring between 100 – 300 microns in length.
2. Where do Demodex live?
The mites can live on all body parts wherever there are
hair roots and sebaceous glands. However, they are most
prevalent in the facial area, especially the nose,
forehead, chin, and cheeks. These areas have the most
favorable living and breeding conditions and provide an
optimum temperature for them to thrive.
The Demodex folliculorum mite can also live in the
eye lash roots and can be the reason for blepharitis,
itching and infections. The hair follicles from the scalp
are also often infected with itching as a result.
The mouth of these mites is like a very sharp needle that
can directly sting into the cells to absorb nutrition.
They like a wet and warm environment and become the most
active in the dark. There are five stages in the life
cycle. After mating on the surface of the skin, they go
back into it and lay eggs, taking bacteria with them and
excreting wastes and secretions, laying eggs and dying
within its layers. After death, their corpses become
liquid and decompose inside the skin.
Demodex is usually 100 – 300 microns long. In simple
terms it is smaller than the tiniest insect but bigger
than a germ.
There are two types, the long and the short. Parasitizing
the facial sebaceous glands at an appropriate temperature,
Demodexes reproduce by a generation every 15 days. The
adult Demodex die soon after the reproduction and the
bodies rot and liquidate inside the sebaceous glands.
Since Demodex spend all their lives inside the sebaceous
glands, they physically and chemically affect the skin,
reducing its immune competence, and causing allergic
reactions in some parts of skin tissues, where red spots
(acne) breaks out. This is sometimes known as adolescent
acne for obvious reasons.
If not treated properly with correct medication, the
inflammation will reoccur. In more serious cases, the
epidermis, or the appearance of skin, will be permanently
injured, scars resembling the texture of orange skin will
be left, hair follicle pores will be enlarged, and the
skin will become thicker due to hyperplasia. Sometimes,
the inflammation even leads to superfluous tumors or
lumps, and red nose.
What hinders the permeation of medicine is the membrane
enclosing the eggs of Demodex?
Therefore, patients are required to apply the lotions
continuously, without any intervals, until a seborrhea
test shows negative, which indicates a full recovery.
Generally, victims of superficial Demodex rosacea caused
by the long Demodex mites should use the lotion for 120 –
180 days, while patients of deep Demodex rosacea caused
by the short Demodex mites should use the lotion for 180 –
The therapies must go on to the end, even if the symptom
of inflammation disappears a few days after first
using the lotion. Demodexin will clear the face usually
within a few days but less than 1 week. There will be a
great deal of excretions and migration during the intial
treatment period. Do not be alarmed by this.
Those who are found to have Demodex existing in their
skin but do not yet suffer from acarodermatitis may
effectively prevent themselves from contracting the
disease by applying the lotion.
According to the research, once the human body is
infected, the Demodex will become parasitic, mainly in
the sebum of the hair follicles of the face where body
touch is frequent, the sebaceous glands are well
developed and the temperature is perfect. They absorb
nourishment, excrete wastes, copulate and lay eggs.
Within 15 days, they give birth to a new generation, the
mites die, rot and liquefy in the skin.
As the Demodex complete the entirety of their life cycle
in the sebum glands and hair follicles, they cause
mechanical and chemical stimulation to the skin. More
and more stimulation will produce an allergic reaction
that leads to inflammation such as popular eruption,
pustules, etc. which we all know as acne and even
If this situation is not followed by correct diagnosis
and treatment, the mites will increasingly multiply and
the inflammation will get worse, leaving scars on the
face, the damaged pores accompanied with widening of the
capillaries, thicker skin, hyperplasis and worse, there
might be vegetation or pimples which will spoil the skin.
What damage can Demodex do?
Demodex mites live inside the sebaceous glands and hair
follicles, sucking nutrients from the hair roots and
damaging the cell walls. After mating they burrow into
the skin, laying eggs, introducing bacteria and infection
to the skin. Throughout the five phases of their life
cycle, these mites destroy the skin by excreting wastes
and secretions, laying eggs and dying within its layers.
After death, their corpses become liquid and decompose
inside the skin.
Research indicates that human Demodex is a
conditional-pathogenic parasite. The disorder occurs as
the result of a large infestation of Demodex mites on the
skin, combined with a weakened immune system. The
physical, chemical and mechanical stimulation of the
skin from the mites can cause the immune system to react
in extreme ways. Local allergic inflammation, erythema,
papules and pustules are all reactions by the immune
The adolescent mite dermatitis and early symptoms of
rosacea are frequently misdiagnosed as adolescent acne.
A sample study has shown that from people with mite
dermatitis (at least 60% of the population), 2.44% have
rosacea; 7.56% have acne-like mite dermatitis. When mite
testing and the accorded treatment are not carried out,
this condition causes increased damage to the normal
health, structure and beauty of the skin. The
destruction of the skin becomes more and more severe as
the condition persists, leaving the facial skin rough
The inflammation will repeatedly occur without timely
intervention, correct diagnosis and effective therapy.
Pathologic changes to the skin, such as enlarged opening
of the hair follicles, widened pores, enlarged and
damaged capillaries, hyperplasia of cells and even
rhinophyma (growth of the nose and central facial areas)
can develop. Given this, it is not difficult to imagine
the extent of the damage that the mites cause.
What are the most obvious signs from Demodex activity?
There are numerous different signs of Demodex activity.
This is not a complete list, rather it contains some of
the most common cases.
One of the most obvious signs of the condition is a
itching, crawling sensation on the face or (and) in the
scalp, but most of the time, there is no itching at all,
and people are not aware they are infested with Demodex
mites. Often, the pores on the nose, forehead, chin and
cheeks become visibly larger. At a further stage, acne
can develop; after some time, the facial skin can become
red in places (rosacea,) enlarging and damaging the
capillaries, thickening the nose (brandy nose), etc.
Tickling sensation on the face. This occurs most
frequently on the lower nose, forehead and cheeks,
especially in the evening and night. This is the highest
period of activity, usually when they mate. Many people
are not aware of this tickle, because it starts gradually
and it becomes an automatic reaction to scratch without
noticing. You may have observed someone repeatedly
scratching their face without realizing it.
Tickle on the scalp. Naturally, there can be also other
conditions that give cause for scratching, like lice and
dandruff. These should be ruled out in order to determine
Hair loss. In some cases, premature hair loss can be
linked with extended Demodex folliculorum activity.
Widened pores. Starts usually on the nose and cheeks.
Acne. Forms include pimples, pustules, papules, popular
Red skin. Usually appears on the lower sides of the nose,
forehead and cheeks.
Itching eye lashes. Many times the eyelashes are thinning
and falling out.
Itching eye brows.
Excess facial oils.
Is teenager acne also caused by Demodex Mites?
Yes, 90% of the teenagers acne is caused by Demodex mites,
10% is bacterial; the change of the hormones at that age
makes the sebaceous glands produce more sebum, making the
facial skin a perfect living and breeding place. They can
now easily multiply and this is translated into infections
I have a greasy skin, will I always have acne?
No, a greasy skin does not mean you need to have acne, a
greasy skin becomes only acne when there are infections,
and the reason for the infections are most of the time
If you eliminate the Demodex mites the infections will
stop and your skin will get smooth and soft again, your
pores will become smaller and an oily skin will be
something from the past. Removing the Demodex mites will
also reduce the infections from shaving to almost nothing.
Is it possible to have a problem with Demodex mites
Yes, many people have problems, in one way or another,
without knowing because there is not a lot of attention
given to them by the medical profession in North America.
The sooner that treatment is begun, the better your
chances are to arrest the mites and prevent them from
causing permanent damage.
Are Demodex Mites contagious?
Yes, Demodex mites are contagious but the parasites
prefer a weakened immune system. This is one reason many
partners who regularly sleep with their mates do not
become infected. However, should the host be suitable,
they are acquired through physical contact with infected
persons; for example through kissing, hugging, using the
same towels, etc. However, not everyone who is infected has
problems with them. It is a fact that the majority of
infected people show no signs of any disease from the
infected people, only around 10% are getting skin
problems. This may be due to a healthier immune system
and/or because of numerous other reasons which are not
so well known at this time.
Infected people with no visible signs can also transmit
the mites to other people. Once infected, it can take
months or even years before the signs of infection
Demodex mites and the beauty of your skin
Even when there are no visible signs of Demodex activity
it is worth to treat yourself and eliminate the mites
before it can become a disease.
A very common result from Demodex mites infection are
widened pores, most of the time starting on the nose.
Eliminating the mites with the Demodexin lotion will
close your pores again and keep your skin healthy.
Another common manifestation is skin flaking which
accompanies the areas where the Demodex have infected and
then moved on.
There are very good cosmetic products these days but what
people doesn’t know is that you actually help the mites
with them, good cosmetics contains a lot of nutrition
and the mites are very happy with them.
Eliminating the mites first will improve your skin so
much more, and the effect of your expensive cosmetics
will be only positive, not helping the mites anymore to
breed and damage your skin.
Losing eye lashes is also many times a result from
Demodex mites' activity which are living in the roots of
the eye lashes.
Why is it so important to do a test to see if you are
infected with Demodex mites?
First of all, it is obvious that you would want to know
if Demodex mites are the reason for your skin problem
before starting the treatment. An accurate test will
reveal the mites' presence.
We always advise people to be tested by a dermatologist
who is experienced in this area. The treatment and
follow up should be with the approval of the
dermatologist. However, in the case where it is not
possible to see a doctor, and you have access to a
microscope, you can easily do the test yourself.
When the test is positive the person will be much more
motivated to start and continue the treatment until the
end. It is also necessary to do a test to find out if
the mites are completely gone after the treatment, even
when the symptoms are gone, otherwise the disease will
How do I do the test (Information for the Dermatologist
In this section we will explain how to determine if you
are infected with Demodex mites and how to find and
count them. In this way you will be able to follow the
progress of the treatment. It is important to do the
treatment until the test result is negative and all of
the mites are gone. Otherwise they will continue to
multiply and the treatment must be repeated. It takes
about 5 minutes for an experienced person to perform the
What you will need:
1. A microscope with a good lighting system and light
condenser, a multiplication of 40 to 60 times is enough
to detect them. In order to see more details you will
need a magnification up to 400X.
2. A tool to scrape the sebum from the face and mix the
obtained sample with the oil on the glass slide. There
are some special tools sold for this purpose but anything
will do, for example a little pointed knife,
doesn’t need to be sharp; be careful not to cut your skin.
3. Household vegetable oil such as bean oil, grape seed
oil, sesame oil, etc. to dissolve the sebum. Do not use
liquid paraffin, glycerin, shampoo oil, etc.
4. Latex gloves to protect your hands from further
infection from the mites, or latex fingers for the
fingers you use to press the sebum out.
5. A small bottle for holding the oil and a pipette to
put drops of the oil on the glass slide.
6. A disinfectant to disinfect the scrape tool.
7. Cotton balls to clean the tool.
What to do:
Taking samples in the different drops of oil and from
different parts of the face will enable you to locate
the originating areas of the mites.
1. First put three separate drops of vegetable oil onto a
2. The doctor should sit face to face with the person
and press the thumb and second finger on one side of the
nose hard enough to squeeze some sebum out and scrape it
off with the mite tool or something similar.
3. Put the obtained sebum in the first drop of oil and
mix it so the sebum will dissolve in the oil and free
the present mites, their larvae and eggs. Label the drop
of oil with the specimen, according to the part of the
face from which the mites were taken.
4. Do the same with the other side of the nose and put in
the same drop of oil and mix.
5. Now press the top of the nose, scrape it and put the
scraping in the same drop of oil and mix.
6. Clean and disinfect the mite tool.
7. Now scrape the forehead between the eye brows, stretch
the forehead skin with your left hand up and starting in
the middle of the fore head, scrape downwards to the
beginning of the nose. Apply enough pressure so that you
have a good sample. Do this a couple of times to ensure
that you have collected enough to produce good results.
8. Put the obtained sample in the second drop of oil on
the glass slide and mix with the oil and once again,
disinfect the mite tool.
9. Now we have to obtain some sebum from the chin.
Clench the jaw and facial muscles to create some tension
on the skin of the chin. Scrape the skin starting from
the lip down and apply enough pressure to obtain some
sebum. Do this a couple of times in different directions.
10. Mix the obtained sample with oil in the third drop of
11. Disinfect the mite tool for future use.
12. Place the glass slide under the microscope and
examine the different drops one by one. Look very
carefully and don’t use too much magnification in the
beginning; 40 to 60X is enough. Increase the
magnification after you find them and want to see more
details. Adjust the light and focus as necessary to see
the living and dead mites, eggs, nymphs and remaining
bodies. Once you know what to look for, they become very
easy to identify and the testing time will take only 5
minutes or so. Counting them will allow you to follow
the progress of the disease by comparing the amount of
mites with the future tests. Record the number that you
find according to type: long (folliculorum) and short
(brevis) from the different areas of the face (different
drops of oil).
If you want to see them move the most dynamic temperature
is between 28- 36 degrees Celsius, the minimum is 25
degrees Celsius. If necessary, warm up the glass slide
in your hands. They can live away from the host
approximately 36-58 hours in a drop of oil.
Larvae and nymphs never move but if you increase
magnification you can sometimes see the mouth of the
nymph moving. If you don’t find any then it is almost
sure you are looking for the wrong things or you did the
test incorrectly and need to do it over. Only discontinue
the treatment when the test results are negative.
How to use the Demodexin lotion?
1. Before application, wash the face and hands with warm
water and a neutral soap or better, a Whole Spectrum
facial bar such as Orpheus or Paean. Wipe the face dry with
a clean towel each time (a slightly moist skin can make
the application of the lotion easier).
2. The easiest way to apply the lotion is
to put some tiny little dots everywhere on the face with
a finger and then gently rub the product into the skin,
it is really not necessary to use a lot, just a tiny bit
is enough. Repeat this procedure as often as possible
but at least 2 times a day, one time
in the morning and one time in the evening, the most
important application is in the evening one. If it is possible
to use more often reapply after the lotion is no longer
evident and the skin is completely dry again. The lotion
acts as a moisturizer and the skin will be soft and supple
while the lotion is working. Once the skin becomes
evidently dry, then reapply until dry again.
3. It is very important to cover the neck and upper chest and
back area as well during the initial treatment phase as
the mites will attempt to migrate.
4. It is a good idea to change out your linens each day
to prevent reinfestation. Disinfecting thorougly your
linens will help prevent the mites from re-infesting your
Try to avoid the use of cosmetics as much as possible
during the treatment. While using the lotion externally
one can take 5-10 mg of vitamin B2 (riboflavin) 3 times a
day at the same time, in addition, any product that can
boost the immune system can be a help. Many customers
have reported a change in diet is beneficial, reducing
foods that weaken the immune system while increasing
foods that strengthen the immune system.
Even if the symptoms are gone, don't stop treating, the
duration of treatment at least 120 days for Demodex
folliculorum, and at least 180 days for Demodex brevis.
Never use the lotion together with a pharmaceutical
ointment at the same time, alternating use in the morning
in the evening is ok. This lotion can only be applied
externally, oral medication is not permitted.
How long must I continue the treatment?
You have to treat until they are all destroyed. This can
only be seen by doing a test. Even if the symptoms have
disappeared, it does not mean that they are completely
gone. If you discontinue the treatment before the mites
have been eliminated, they will multiply again very soon.
The treatment can take up to one year, but you will
see the results almost immediately and in most of the cases,
when you also suffer from itching skin, this itch will
stop after the first week or so.
To eliminate the long Demodex (folliculorum) you
need continuous treatment for 120 days. For the short
Demodex (brevis) it will take 180 days. Since
without a test you never know if Demodex brevis is
present it is advisable to treat always at least for 360
days to be sure they are all gone, however, the majority
of the mites will be eliminated after one week.
Why does it take so long to eliminate them completely?
It takes so long because they are so difficult to reach
and because the eggs and nymphs cannot be killed.
Demodex folliculorum is the easiest to destroy
because they live in the hair follicles and come
regularly out of the skin to mate on the surface.
Demodex brevis mites live deeper
in the sebaceous glands and don't surface as often;
they are much more difficult to reach, that is why
Demodex brevis takes a longer time to eliminate.
The ovum and nymphs are always in a deeper part of the
skin and are covered with a membrane which nothing can
penetrate except essential oils. The ovum and nymphs
cannot be killed with pesticides, not with
Ivermectin, mustard plaster or whatever. The time from copulating until a
new generation hatches is between 15 to 20 days. So, it
is very important to treat in a continuous way to catch
the adults and prevent them from mating again.
Can there be setbacks?
Yes, it is possible to have setbacks even after several
days or months of treatment. When the mites die, they decompose
inside the skin and cause infection there. Different
people have different levels of reaction to the infection.
This is the most difficult period for acne and rosacea
suffers, because they sometimes think that the treatment
is not working, but on the contrary, it means that the
lotion is working well and the mites are being killed.
It is very important in this stage not to become
discouraged and to continue the treatment without
interruption. This period will last not long. Know that
you skin will clear up and get better soon.
Can I use make-up while treating?
It is better not to use make-up or as little as possible
while treating. The goal is to kill all of the mites. If
you use make-up or something else at the same time, the
action of the lotion is weakened and the treatment will
be longer. Of course, if needed you can use make up once
in a while.
Why the tickle does become worse in the evening and
Demodex mites are more active in the dark. They are
genetically programmed to surface in the evening to
breed, probably to increase there survival chances (host
is sleeping). This explains why the tickle/itch gets
worse in the evening. There is much more movement on the
surface of the skin at that time.
Do I need to take vitamins during the treatment?
Yes, it is a help if you take 5-10 mg of vitamin B²
(riboflavin) 3 times a day during the treatment, in
addition, everything that can boost your immune system
is a help.
How long do they live outside the body?
Demodex mites die soon in a dry environment. They can
only live for a couple of hours away from the host. In a
wet environment, like towel, this can be longer, and in
a drop of oil for example they can live sometimes up to
Is there a need to take special precautions in the
household while treating?
Not so much, Demodex mites will eventually die soon when
away from the body, but they can sometimes live longer
without a live host in a humid environment like towels
etc., so always use your own towels and personal
accessories; also try to change your pillow case every
day and if possible your sheets as well.
Try to avoid contact with other infected persons even
when they show no visible signs of having the mites;
they can infect you again. If in doubt, your partner
should also be tested for Demodex mites and if infected,
do the treatment, otherwise you will become re-infected
by means of physical contact, pillows, bedding, etc.
Please don't over react if your partner has no visible
signs like acne, rosacea, itch, etc. In this case, wait
first till the treatment improves you so you are sure
Demodex mites were your problem, then later you can try
to find out if physical contact with your partner makes
you worse again and treat him/her if necessary.
Try to avoid facial contact with your pets and wash your
hands after petting them.
What to do after the treatment?
Normally you don’t have to do anything. Gone is gone but
it is easy to become infected again by contact with
other people, towels, your partner (if not treated),
Sometimes there is a residual bacterial infection that
is evident even if the mites are gone. Use one of the
Paean products for bacterial infections caused by the
mites or other reasons to eliminate this condition. For
extra-sensitive skin sufferers use Charis facial products.
In addition, for long-time sufferers with damaged and/or
scarred skin, use Dionysus products of clear up damaged
and/or scarred conditions on the face caused by the
Try to minimize physical face contact with other people
and don’t use their personal things like towels etc.
It is a good idea to use one of the treatment products
on some kind of regular basis before going to sleep to
prevent them from returning like for example every other
day only in the evening.
At the first signs of re-infection take a test as soon
as possible. If the results are positive, restart and
continue the treatment until the mites are gone again.
Can there be itching all over the body?
Yes, while demodex mites can live anywhere on the body
where there are sebaceous glands, tickle and spots can
occur on other areas of the body because of an allergic
reaction by one’s immune system to infection from the
mites, however, normally this can only happen when the
immune system is really weakened, like for example AIDS
patients. Acne on chest or back is more likely to happen because
of Demodex mites.
Why they can not be treated effectively with pesticides
Human pesticides are harmful to the health of your skin
and require in case of Demodex mites to a long period of
treatment for your facial skin with generally poor
results. The mites burrow deep into the tissue of the
skin and are well hidden inside the hair follicles and
sebaceous glands, making them very hard to reach. You
cannot kill the eggs and nymphs because they are
enclosed with a membrane that seals them well; also,
pesticides can not penetrate this seal.
Using a pesticide a couple of times does almost nothing
because you only kill the ones you can reach and every
day new ones appear, ready to breed. The most successful
approach is continuous treatment with a safe to use
product. This assures that you are killing all of the
mites as they come to the skin’s surface and over time
it will take care of the ones who don’t.
Can Demodex mites cause problems in the eye lashes?
Yes, Demodex mites can cause severe problems in the eye
lashes. Many woman are loosing there eye lashes because
of Demodex activity, Extreme tickling, redness because
of infections and even blepharitis. Only by treating the
face to eliminate the Demodex mites is, most of the time,
enough to get rid of this problem; in some extreme
cases, additional treatment of the eye lashes can be
As a matter of caution, never use any of the products
from the website in your eyes or eye lashes. They are
safe to use under your eyebrows and eye lids. Treatment
of the eyes and the surrounding areas requires very
careful use. You must first be examined by a
physician who specializes in this field. Generally, a
prescriptive ointment will be recommended. To repeat:
Always consult with your physician before you use any
kind of medication on your eyes.
My doctor tells me I am delusional?
This happens every day, except in Eastern Europe and Asia,
almost all dermatologists in North Ameria don’t recognize
or take Demodex mites into consideration when an itchy or
crawling feeling on the face or/and scalp occurs. In the
rare cases they indeed diagnose Demodex mites the only
thing they can do is treating with pesticides who are
poisonous and very bad for your skin. Most of the time,
pesticides only help a bit and are not able to eliminate
them completely so they just start to breed again and the
symptoms stay. The reason why some people are getting
troubles with those mites and others not is not well known,
but has probably to do with a change in the immune system.
Doctors simply don’t know how, or don’t want to test for
those mites. It is a pity because it is very simple and
takes only a couple of minutes. That is how it works in
the Western medicine, if they can’t prove or they don’t
know, it is not there, and sending the people home with
the message they are delusional happens many times.
Especially people with a lowered immune system can become
suddenly a victim from those mites. If you have a facial
skin problem and you are not sure if Demodex mites are
the reason, it is a good idea to mail us first with the
explanation and history of the problem, in that way we
can help and advice you much better.
Dogs and red mange, infestation from Demodex mites
We are not familiar with treating pets but according to
people who have already used our products to treat their
dogs against Demodex mites, our products seems to work
great, even better then the pesticides usually used for
pets. If you want to treat your dog with non-poison safe
lotion, this is the solution.
Demodicosis and Associative Diseases
Translation of a article published in "Bulletin of the
Academy of Sciences of the Republick of Kazakhstan",
1992, No. 4, pp.84-88
Demodecosis as an independent disease has not yet well
investigated. However, in the past decades the interest
in this and other mites diseases has considerably grown
(A.A.Antonyev et al.., 1988; R.D.Zhaxylykova, 1990)
The clinical picture of the demodicosis from the moment
of infestation to development of various complications
has not been adequately described. Moreover, up to now,
the issue of pathogenic role of the mites Demodex upon
the human beings remains disputable.
Material and investigation methods
In the laboratories, the Demodex mites were detected in
almost all 6547 patients examined. In the investigation,
we used the methods developed by our team (R.D.
1: Direct micro scoping of the skin and mucous membrane
surfaces in vivo by application of the adapted devices
magnifying at least 50 times.
2: Rubbing in the pores of the skin with rapidly
penetrating anti parasitics that cause destruction of
the Demodex in the place of their habitat, and thereby
release the allergenic components on which the local
allergic reaction is being developed in the form of an
edema of the connective tissue capsule, this leads to
appearance of a visible papule - demodicosis focus.
Moreover, we applied the universally known methods of
scraping (B.P.Baksht,1966) and epilation (M.M.Mukhina,
The 790 patients infected with Demodex were examined by
the provocative method of detection of the Demodex
colonies (R.D.Zhaxylykova, M.K.Kenenbayeva, 1990)
Amongst the papules detected in all the patients
examined, 873 colonies of the mites were subjected to
enucleation and to subsequent micro scoping. In 93% of
them were Demodex mites detected, in 0,4% - Sarcoptes
scabiei, in 6,6% - colonies of by us, unidentified mites.
Moreover, 10 persons with healthy skin were examined by,
for us, accessible methods and in which the mites and
their colonies not have been found.
A long-term dynamic observation was conducted over 342
patients infected by Demodex, infestation of these
patients occurred through natural conditions more then
15 years ago till they became the sick persons with the
laboratorial confirmed demodicosis. Besides that,
demodicosis was also produced experimentally on a
volunteer who had a healthy skin and on two cats which
preliminary were thoroughly prepared for the experiment
in witch the cats, during a period of tree months where
bathed every day with soap and brush. Infestation of the
volunteer was executed through the pre-boiled wisp of
bast, on which the Demodex mites were taken from the
"butterfly" region from the face a patient having
laboratorially confirmed demodicosis on the face.
By use of anti parasitics, there were 151 patients
successfully cured who had various clinical
manifestations and complications (so called clinical
masks) /R.D.Zhaxylykova, 1990/ of the demodicosis (see
Results of the investigations and discussion
Several investigators /A.K.Akbulatova, 1966; T.Rufli,
G.Mumcuoglu, 1981/ marked in their papers at the high
percentage of the Demodex infestation of the skin of the
dermatologic patients and of "practically healthy"
persons. We have a different point of view upon this
fact. Among the infected by Demodex, in 62% of the
examined persons there were clearly found expressed
subjective sensations from the part of the skin. At the
purposing questioning this percentage increased up to
84%. Periodical slight strokings, mainly of the face
skin, scratchings that were observed in almost all
examined patients allow us to speak about availability
of the subjective symptoms in 100% of the patients under
observation. Upon examining the subclinical and clinical
manifestations of the demodicosis or its complications
were found in all persons infested by Demodex. Absence
of the mites in the skin of the examined persons with
healthy skin testifies correctness of the clinical
observations being carried out. Also this is confirmed
by effective antiparasitic treatment of the patients, to
which the specialists of different profiles gave
different diagnosis. Absence or sharp decrease in
percentage of detection of the mites in the skin of the
treated patients (see Table) together with the positive
dynamics of the clinical picture allow us to conclude as
per their involvement in origination and development of
the indicated diseases. However we consider necessary to
continue investigations in this aspect with the
acarological observation of the affected ("shock")
organs and tissues.
As per mechanisms in development of allergic
complications due to demodicosis, our points of view
completely coincide with points of view and conclusions
of the allergologists /V.I.Pytsky, et al.,1984/.
Long-term, let it be even symbiotic (as the
dermatologists and some other specialists consider)
presence of Demodex in the human being skin pores in
considerable amounts (from 1 sq. cm of the skin there
were picked out up to 500 specimen of the Demodex /Yu.S.
Balashov, 1982/) may cause sensibilization of the host`s
organism. Effectiveness of the antiparasitic therapy
makes it possible to conclude that over 151 years from
the moment of detection in the glands of the skin of the
human being in 100% of the examined persons the Demodex
could transfer from the symbiotic to the parasitic mode
of life. A similar phenomenon can be observed in the
microcosm not infriquently /K.I.Skryabin et al., 1934/.
This fact can explain the infectious nature, being found
by the epidemiological investigators, of growth and
dissemination of allergy and other, so called
noninfectious, diseases /A.M.Vikhert, A.V.Chaklin, 1990/,
some of which are listed in the Table given in this
The demodicosis in 100% cases are inherited from the
mother /Yu.S.Balashov,1982/. Our clinical observations
have also shown 100% infestation by Demodex of the
children of all ages beginning from the first days of
their life. Therefore we consider that demodicosis and
the associative diseases with participation of the
Demodex began to affect the younger persons than it was
earlier /K.S.Ternovoi et al., 1990/. Our investigations
show that majority of the famous allergenes destroy the
microscopic mites present in the organism of the patient
with allergy. In this case a great amount of allergene
components of the mites are being released, to which the
host organism has been sensibilized. This fact was
considered by us during treatment of the allergologic
patients. For complete deliverance of the patients
organism from the mites we used the "allergenic" for
them earlier factors (food, medical preparations,
pollen, etc.), which gave us possibility to reach
complete liquidation of allergy in 91% of the
allergologic patients. Diversity of clinical
manifestations and complications of the demodicosis,
from one part, may be the result of high self-organization
of such microscopic organism as the mites Demodex /V.I.
Zakharov, 1972/. From the other part, as it is known
from literature, the mites can transfer on their bodies
the smaller organisms: viruses, bacteria, fungi, etc. /
Yu.S.Balashov,1982/. This may be the reason of
development of the associative diseases, being caused,
for example, by the Demodex and by the definite virus
(including AIDS), by the Demodex and by the definite
bacterium, etc. There may be very many such combinations,
therefore clinical manifestations of the associative
disease may be very different. Availability of the
pricking-sucking-cutting mouth apparatus in the Demodex
/Yu.S.Balashov, 1982/ promotes the appearance of the
above-listed combinations of various associations
(bacteria, viruses, etc.). Detection in one and the same
patient of three varieties of the mites allows to speak
about existence of the diseases caused by association of
different mites with different microorganisms. The afore
said may be added with information about high
invasiveness of people to helmiths /N.N.Glamazanova, 1987/.
Taking into consideration the above-mentioned data there
may be supposed a possibility of wide spread of
associative diseases, in which the Demodex may be an
active etiological component. The high percentage of
invasiveness of the skin and mucous membranes by the
Demodex together with the available information in the
literature gives us possibility to ascertain the
availability of the demodicosis pandemic. It would be
more correct to say about the pandemic of the
associative diseases, in which the Demodex is the
etiologic connecting base.
The demodicosis, that is not taken into consideration in
the medical practice, considerably complicate the cause
of famous infectious and noninfectious diseases.
Availability of pandemic of the demodicosis and the
associative diseases requires consolidation of the
efforts of biologists, parasitologists, veterinary and
medical specialists for liquidation of all manifestations
and complications of these diseases.
In the original this paper was published in the journal
"Bulletin of the Academy of Sciences of the Republic of
Kazakhstan", 1992, No 4, pp.84-88.
Demodexin ingredients: 100% NATURAL NON-TOXIC,
2.5% ACTIVE INGREDIENTS: ESSENTIAL OILS,
BASE: ORGANIC JOJOBA EMULSION
TESTIMONIAL BY JH (March 10, 2013):
Here is some of my history with the problem and products
I have used the demodexin crème since last February 2012. When I started it I had already been using apple cider vinegar in the evenings when I could feel the crawlies. I noticed a difference soon with he demodexin crème, but I had much more eruptions that literally were like ‘holes’ starting in my skin….something I’ve never had at all. I called Michael he said the mites were escaping from under my skin to get away from the crème’s toxin. I kept using the crème.
When the holes came it would take about 4 -5 days for
them to heal again, while using the crème, and picking
off the white ‘mass’ which is the mite debris. The only
thing that would keep the healing spots ‘soft’ to not be
like a hard scab…was using the Charis Step 2 cleansing
hydration, and I did not use it to wash, just to cleanse
by rubbing into area, which kept the skin and healing
all soft, much better during healing. And I wanted to
allow for the hole to close on it’s own so that the
mites would continue to flee. I used the crème all
around hair line, in eyebrows, all neck, and all over
chest, because the mites will go and hang out somewhere
and then come back when/if the skin is habitable again.
The main area I noticed for al these months and still
have it slightly is the ‘white debri’ mimics he skin so
much it looks like real, but just underneath even a tight
healthy pore was a film so slight going from check to
check and all over nose. I have removed a layer almost
every day since last February. It is NOT skin, so
pushing it out, scraping then putting more crème---I have
done this an average of 3-6 times per day, plus at
bedtime and morning right away for all these months….not
missed 1 day.
In May my skin had terrible eruptions and I hibernated in
the house doing work but not going out.
Also, ALL this time I used antibiotics every day most
days because the holes could get bacteria, and I needed
to use the medication to reduce the breaking up of the
skin and possible infection that ‘they’ call rosacea.
The main area mites are very resistant to leave is the
nose, under nose….the crème there can wear off much more
quickly, and even 1 week not paying attention to that
area in particular I see they are making headway.
I feel one or two while sitting here, but I scratched
and that must kill them because scratching the skin there
stops the crawling feelings right away.
I have spent 1 or more hours every single day on this
since last February. I have changed my pillowcase every
single night too. I keep a stack of 10 in a basket by the
I also used the scar oil—charis step4 sensitive skin
repair serum. I use on all spots, holes, or wrinkles on
my face. I have not kept any scar that if not using the
holes would scar my light skin. There is a very vague
shadow on one or two places that no one else would detect
and those would have been scars if not for this scar oil.
Michael sent me ‘pure’ 100% demodexin oil without any
dilution. I am putting it only on my nose area and the
persistent place on my left cheek beside lips. This is a
fatty part of the face. This is VERY potent oil that at
first made me feel nauseated. It is a neurotoxin so I
am careful to add to some emulsion. I believe it works
as a added attack.
I am unsure if these will ever be completely gone, but I
will use crème for my life I think. My skin that is
unaffected glows and is radiant for my age look much
younger and much of that is due to how great the crème is
for ALL the skin. If I could use it all over my whole
body I would, but the expense!!
So my only products from wholespectrum are:
Demodexin pure oil
Chars hydration milk step 2
Charis step 4 skin repair oil
Vitamin Enriched Facial Hydration Face Mist
The scrub pads (these help scrub out the mite debris)
If You are not allergic and can afford it, I would put 5
times the amount per day on your skin, use scrubbing
pads to clean off dead skin cells and mite debri, (I
also use a eyebrow pluckier to literally pluck out some
debris on the skin during a breakout and then use charis
crème to keep the place soft, then put on the demodexin
crème, then the scar oil. I use all of them at once) I
am very careful with the plucker and literally ‘pull’
off what looks like skin, but it is only debris escaping
the skin…..15 years of this she*t. It is imperative to
keep watching it every day as often as possible. I also
pinch out the debris like they do when getting a facial.
It’s all white and clearly not whiteheads.
I am not done, I have a thin layer still taking it slow
(no other way anyway) and letting this come out a little
bit every day.
I have not had to take any antibiotic for 2 months now
at all. I have not had any holes or breakouts since 3
weeks and it was minor but still persistent mites in a
panic hanging on.
I will never give up this fight, it is better and my
skin looks great. I do know I have to continue for a
while. Will keep in touch.
Let me know how you are doing. And thanks for emailing
Take care and Good luck!
TESTIMONIAL BY MR (January 18, 2013):
I am writing to tell you that I am having remarkable
results using this lotion. I began using the lotion on
November 13th and have used it twice a day since although
I had to use it very sparingly in Maui (Dec. 17-Jan 9) as
I was running very low.
My symptoms continued unabated for the first three weeks
and my itch grew worse at night. It was terrible as I
could not sleep. By the middle of December my symptoms
began to diminish and with each day my results improved.
Since I have been home (Jan 10) the last eight days I
have been experiencing nothing short of a miracle as 95%
of my symptoms are gone. My itch is almost non-existent
and I can finally sleep. I have no face, nose, etc.
irritation, no specs coming out of my pores, no new
papules and pustules. I am so happy I almost can't
believe my good furtune as my life has been hell for the
past 1 1/2 year.
I know it is still early days but I have never
experienced such a relief since I contacted demodex
folliculitus and I just feel so very normal now; I am
loving it. I will continue to use the lotion until it
is all used up. My supply will probably last two more
months at least.
I wanted to let you know my good news and to thank you.
Will let you know how I am in two months time.
Thank you so much.